![]() Girls, women, and prepubertal boys may be negatively affected by AA hypersecretion in contrast to adult men. Although adrenal androgens do not appear to play a major role in the fully androgenized adult man, they seem to play a role in the adult woman and in both sexes before puberty. The production of T by the adrenal glands is minimal ( 7). Although these steroids have little androgenic activity, they provide a pool of circulating precursors for peripheral conversion to more potent androgens (e.g. DHEA and DHEAS are secreted in greater quantities than the other adrenal androgens. ![]() ![]() They include dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEAS), androstenedione (A4), androstenediol (Α5) and 11β-hydroxyandrostenedione (11βOHA4) ( 1). Adrenal androgens (AAs), normally secreted by the fetal adrenal zone and the zona reticularis of the adrenal cortex, are steroid hormones with weak androgenic activity. ![]()
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